"Looking to beef up your application security? Take a look at Novell AppArmor, a Linux application security framework included with SUSE Linux Enterprise 10. AppArmor gives you network application security via mandatory access control for programs, protecting against the exploitation of software flaws and compromised systems. AppArmor includes everything you need to provide effective containment for programs (including those that run as root) to thwart attempted exploits and even zero-day attacks."
See also Chris Brown at Linux.com - Protect your applications with AppArmor.